Prostate Cancer Initial Treatment Options

These prostate cancer treatment options is based on the stage of prostate cancer

Low risk prostate cancer treatment management (Stage 1 and 2A):

1. Active Surveillance
2. Prostatectomy
3. External beam radiotherapy alone
4. Brachytherapy
5. Expectant Management

Intermediate risk prostate cancer treatment management (Stage 2B and 2C):

1. Neoadjuvant Androgen Deprivation Therapy (ADT) and radical external beam radiotherapy (undergo ADT for 2-8 months first and then radiotherapy or together with radiotherapy)
2. Dose-escalated conformal external beam (3D) radiotherapy
3. Prostatectomy
4. ADT as primary treatment if contraindication to radiotherapy and prostatectomy
5. Expectant Management
6. Observation (for patients with significant morbidity or poor life expectancy)

High risk prostate cancer treatment management (Stage 3 and 4):

1. Neoadjuvant ADT and external beam radiotherapy (including elective treatment of pelvic lymph nodes) PLUS 2 years adjuvant hormone treatment
2. Prostatectomy (for highly selected patients with low volume disease; not suggested for patients with prostate cancer stage 3B and 4) Post operative radiotherapy and/or Androgen Deprivation Therapy (ADT) may be required
3. Androgen Deprivation Therapy (ADT) as primary treatment in very high risk patients with low chance of cure
4. Active Surveillance(for patients with significant morbidity or poor life expectancy)

Main article - Prostate Cancer Treatment